
The Doors - When The Music's Over
Years pass, but some things remain unchanged - is that possible?
Despite my doubts, I can say that The Doors created a great deal of great music that is still worth listening to today.


"From the comments I heard on dutch tv, I made up that they deliberately pulled down some buildings in order to prevent these building from collapsing towards other buildings (domino-effect)".
"yeah i heard it too in the portugues tv..but the thing is how could they made a controled demolishion a few hour after the attack? that thing needs lots of time to be prepared".
U.S. Military Website Used For Domestic PropagandaSubject: JOHN GEBHARDT of IOWA
John works at the Cargill plant in Eddyville, ! Iowa.
Wouldn't it be fitting if this went completely around the world!.....
John Gebhardt's wife, Mindy, said that this little girl's entire family was executed. The insurgents intended to execute the little girl also, and shot her in the head...but they failed to kill her. She was cared for in John's hospital and is healing up, but continues to cry and moan. The nurses said John is the only one who seems to calm her down, so John has spent the last four nights holding her while they both slept in that chair. The girl is coming along with her healing.
He is a real Star of the war, and represents what America is trying to do.
This, my friends, is worth sharing. Go for it!! You'll never see things like this in the news. Please keep this going. Nothing will happen if you don't, but the American public needs to see pictures like this and needs to realize that what we're doing over there is making a difference. Even if it is just one little girl at a time.
James Gates U. S. Navy
"The young infant had received extensive gunshot injuries to her head when insurgents attacked her family killing both of her parents and many of her siblings. The chief had a knack for comforting her and they often would catch a cat nap together in a chair".
Previous studies have shown that a protein called amyloid beta is toxic to neurons. Amyloid beta accumulates in the brains of people with AD, forming deposits called amyloid plaques that are a hallmark of the disease. Many investigators are looking for ways to reduce the buildup of amyloid in the brain, with the hope that such a treatment would slow or halt AD.
In the new study, investigators report a way to remove amyloid beta from the brain by introducing another protein that binds to amyloid beta and pulls it from the bloodstream. The amyloid is then removed by the kidneys, liver, and spleen. The investigators, led by Berislav Zlokovic, M.D., Ph.D., of the University of Rochester Medical Center in New York, compare the treatment to a sink because it essentially drains the toxic protein away. The work was funded in part by the National Institute of Neurological Disorders and Stroke (NINDS). It is reported in the September 2007 issue of Nature Medicine.
Dr. Zlokovic and his colleagues studied a protein called soluble low-density lipoprotein receptor-related protein (sLRP). They discovered that sLRP normally binds to and inactivates 70 to 90 percent of the amyloid beta found in the body. However, levels of sLRP were approximately 30 percent lower in blood from people with AD than in healthy people. Much of the remaining sLRP in people with AD was damaged by a process called oxidation. The damaged sLRP was much less effective at removing amyloid beta from the bloodstream than the normal protein. "The binding capability is almost all lost," Dr. Zlokovic says.
The researchers developed a super-potent version of sLRP, called LRP-IV, and injected it into mice to see whether it could mimic the effects of normal sLRP. The treatment bound to amyloid beta and prevented it from entering the brain. It also reduced the toxic amyloid that was already in the brain.
“There is a balance between amyloid beta in the brain and in the rest of the body,” Dr. Zlokovic explains. “If we lower the level of amyloid beta circulating in the blood, the levels in the brain go down, too.” The effect is similar to the way statin drugs remove cholesterol from the bloodstream and help to prevent heart disease, he adds.
Dr. Zlokovic's research should be thought of as a "proof of concept" study in that it doesn't introduce any additional theory to how Alzheimer's Disease works, or how can be treated, but it does confirm that by lowering amyloid beta levels in the blood a drop of amyloid beta in the brain results.
Read below for additional information about the relevance of this study:
The study is the first to show that people with AD have reduced levels of sLRP and that sLRP helps remove amyloid beta from the blood, Dr. Zlokovic says. It is still unclear why sLRP levels are lower than normal in people with the disease, he adds. The researchers tested 40 people with AD for mutations in the sLRP gene and did not find any abnormalities. However, previous studies have shown that AD causes oxidative damage to many proteins. The oxidative damage to sLRP may trigger its breakdown, as well as inactivating it.
The findings suggest that LRP-IV might eventually be useful as a therapy to prevent or stop AD in people. However, the investigators first need to develop a form of the protein that could be tested in humans. They also need to conduct many additional studies to evaluate the drug’s safety and to learn more about how it works.
Taken into context against the backdrop of additional studies it seems reasonable to suggest that successful preventatives, and treatments for AD will be available within ten years.
Dear Mr. Prophet,
I saw your August 27, 2005 blog's photograph of the
Leonard Volk bust of Abraham Lincoln. It's a beauty!
I had read the story of Volk making his head cast, but
had never seen the resulting bust.
I am writing (and publishing) a book about Lincoln and
would like to include your photo (converted from color
to gray-scale). I'll give you credit, of course, and
I'll send you a copy of the book, too, which I expect
will be out this calendar year. Want me to include
your URL in the photo credit? It is your photo,
right? :-)
Thank you, and regards,